An Improved Process for the Palladium-Catalyzed C–O Cross-Coupling of Secondary Alcohols

S.L.Buchwald 课题组 2020年发表于 Org. Lett. 期刊的文章。
DOI: 10.1021/acs.orglett.0c01668

简要介绍

富电子芳基溴与芳基氯反应性存在差异!

Graphical Abstract

GA

Ligands of secondary alcohols

Ligands

Literature precedents

Literature

General catalytic cycle of Pd-catalyzed C-O cross-coupling

Examples

Fig_1
Fig_2

See article for more examples